Let's Talk Micro

Dr. Rodney Rohde returns to the podcast! This time he joins Luis to talk about dengue. You might hear reports about increases in cases in some areas, so it was a good time to talk about it. What is dengue? What type of virus it is? Vectors? Prevention? Is there a vaccine? Tune in to learn more about this virus.

Link to Dr. Rohde's dengue article: https://asm.org/articles/2024/august/dengue-is-spreading-is-warmer-weather-to-blame

More information about dengue: https://www.cdc.gov/dengue/index.html

Link to Dr. Rohde's Podcast: https://www.contagionlive...

If you work in a clinical microbiology laboratory, you might have worked with bone and joint samples. In this episode we dive deeper into bone and joint infections. Luis is joined by Dr. Joan Gomez-Junyent, an Infectious Diseases physician at Hospital Del Mar in Barcelona, Spain. Dr. Gomez goes over different types of infections. What organisms are typically seen? Is there a typical treatment of choice? How about antimicrobial resistance? Tune in to hear Dr. Gomez go over these questions and more.

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Season 4 is here! Tune in for the first episode. Luis talks to Dr. Paul Hergenrother about lolamicin. Dr. Hergenrother is a Professor of Chemistry at the University of Illinois in Urnaba-Champaign. He was previously a guest in the podcast (fabimycin episode) and this time he returns to talk about another potential antibiotic candidate: lolamicin. What is lolamicin? What is the mechanism of action? What organisms does it have activity against? Does it affect the gut microbiota?

Link to Dr. Hergenrother's article: https://www.nature.com/articles/s41586-024-07502-0

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Originally published in May 26, 2022, in this episode Luis continues going over beta hemolytic strep: this time Streptococcus anginosus group. What are the species that comprise this group? What is the Lancefield group? What about biochemicals and morphology? Have you heard of Streptococcus pseudoporcinus? Tune in to find out.

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Originally published in November 30 2023, in this episode, Dr. Pei Zhou from the Duke University School of Medicine joins the podcast and talks to Luis about LPC-233. This is a compound that shows bactericidal activity against some gram-negative rods. LPC-233 is an LpxC inhibitor. What is LpxC? How does LPC-233 works? What are some challenges of developing LpxC inhibitors? Tune in to find out.

Link to article: https://doi.org/10.1126/scitranslmed.adf5668

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Originally published on October 13, 2022, in this episode Luis talks to Dr. Paul Hergenrother from the University of Illinois. Dr. Hergenrother talks about Fabimycin, an antibiotic candidate for gram negative bacteria. What is Fabimycin's mechanism of action? To which bacteria does it show activity against? Any intrinsic resistance? Tune in to find out.

Link to article: https://pubs.acs.org/doi/10.1021/acscentsci.2c00598

Questions? Feedback? Send those to letstalkmicro@outlook.com

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A great way to end season 3! In this episode Dr. Cullen Lilley talks to Luis about his textbook : A Concise Review of Clinical Microbiology . Dr. Lilley is a pathology resident, with a Microbiology background, and a Let's Talk Micro listener! Tune in to learn about what is in this microbiology textbook, what is Ace my Path, what are the roles of a pathologist and more.

Link to Ace My Path: https://www.acemypath.com

Link to textbook: https://a.co/d/gGDiZ8Z

Questions? Feedback? Send those to letstalkmicro@outlook.com

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In the laboratory we routinely use molecular testing to identify organisms in blood cultures. We also incubate body fluids in blood culture bottles. What if we could use those same tests to identify organisms from body fluids? In this episode Christina Cox and Joel Mortensen join the podcast to talk about this. They performed a study where they used the cobas® eplex system (GenMark) to identify organisms recovered from sterile body fluid cultures. Tune in to hear about the results and the applications of this in the clinical laboratory.

Link to article: https://doi.org/10.1128/jcm.01611-23

Throwback Thurdsday! This week shows an episode originally released in 2022 where Luis talks to Andrea Prinzi about respiratory cultures. What are the types of respiratory cultures? What are the pathogens? What is the significance of yeast in respiratory cultures? Sputum rejection? Tune in to this episode to learn more about these cultures.

Link to article about sputum rejection that Dr. Prinzi mentions in the episode: https://journals.asm.org/doi/pdf/10.1128/jcm.16.4.627-631.1982

Questions? Feedback? Send those to letstalkmicro@outlook.com

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In this episode Luis is joined by Dr. Crystal Icenhour to talk about the microbiome, more specifically, the human microbiome. What organisms typically make up the microbiome? Do they change between areas of the body? What are some applications for the microbiome? Tune in for another great episode.

Questions? Feedback? Send those to letstalkmicro@outlook.com

Want to support the podcast? Here's how:

Venmo: https://venmo.com/u/letstalkmicro

Buy me a Ko-fi: https://ko-fi.com/letstalkmicro